1SD1
STRUCTURE OF HUMAN 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE COMPLEXED WITH FORMYCIN A
Summary for 1SD1
Entry DOI | 10.2210/pdb1sd1/pdb |
Descriptor | 5'-methylthioadenosine phosphorylase, (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol (3 entities in total) |
Functional Keywords | methylthioadenosine phosphorylase, purine nucleoside phosphorylase, purine salvage, formycin a, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q13126 |
Total number of polymer chains | 1 |
Total formula weight | 31544.29 |
Authors | Lee, J.E.,Settembre, E.C.,Cornell, K.A.,Riscoe, M.K.,Sufrin, J.R.,Ealick, S.E.,Howell, P.L. (deposition date: 2004-02-12, release date: 2004-05-18, Last modification date: 2024-02-14) |
Primary citation | Lee, J.E.,Settembre, E.C.,Cornell, K.A.,Riscoe, M.K.,Sufrin, J.R.,Ealick, S.E.,Howell, P.L. Structural Comparison of MTA Phosphorylase and MTA/AdoHcy Nucleosidase Explains Substrate Preferences and Identifies Regions Exploitable for Inhibitor Design. Biochemistry, 43:5159-5169, 2004 Cited by PubMed: 15122881DOI: 10.1021/bi035492h PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.03 Å) |
Structure validation
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