1SCK

K236L mutant of hydroxynitrile lyase from Hevea brasiliensis in complex with acetone

1SCK の概要

• エントリーDOI: 10.2210/pdb1sck/pdb
• 関連するPDBエントリー: 1qj4 1SC9 1SCI 1SCQ 1yas 2yas 3yas 4yas 5yas 6yas 7yas
• 分子名称: (S)-acetone-cyanohydrin lyase, SULFATE ION, ACETONE, ... (4 entities in total)
• 機能のキーワード: alpha-beta hydrolase fold, substrate complex, catalytic triad, lyase
• 由来する生物種: Hevea brasiliensis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29688.91

構造登録者

Gruber, K.,Gartler, G.,Krammer, B.,Schwab, H.,Kratky, C. (登録日: 2004-02-12, 公開日: 2004-06-29, 最終更新日: 2023-10-25)

• 主引用文献: Gruber, K.,Gartler, G.,Krammer, B.,Schwab, H.,Kratky, C.; Reaction mechanism of hydroxynitrile lyases of the alpha/beta-hydrolase superfamily: the three-dimensional structure of the transient enzyme-substrate complex certifies the crucial role of LYS236; J.Biol.Chem., 279:20501-20510, 2004; PubMed: 14998991; DOI: 10.1074/jbc.M401575200

実験手法

X-RAY DIFFRACTION (1.7 Å)