1S8D

Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9-3A

1S8D の概要

• エントリーDOI: 10.2210/pdb1s8d/pdb
• 分子名称: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, gag peptide, ... (4 entities in total)
• 機能のキーワード: ctl, cytotoxic t lymphocytes, hiv, human immunodeficiency virus, mhc, major histocompatibility complex, pmhc, peptide-mhc complex, rmsd, root-mean-squared deviation, siv, simian immunodeficiency virus, tcr, t-cell receptor, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: Q9TQH5; Secreted: P01884
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 44491.37

構造登録者

Martinez-Hackert, E.,Anikeeva, N.,Kalams, S.A.,Walker, B.D.,Hendrickson, W.A.,Sykulev, Y. (登録日: 2004-02-02, 公開日: 2005-09-06, 最終更新日: 2023-08-23)

• 主引用文献: Martinez-Hackert, E.,Anikeeva, N.,Kalams, S.A.,Walker, B.D.,Hendrickson, W.A.,Sykulev, Y.; Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes.; J.Biol.Chem., 281:20205-20212, 2006; PubMed: 16702212; DOI: 10.1074/jbc.M601934200

実験手法

X-RAY DIFFRACTION (2.2 Å)