1S5I

Fab (LNKB-2) of monoclonal antibody to Human Interleukin-2, crystal structure

Summary for 1S5I

• Entry DOI: 10.2210/pdb1s5i/pdb
• Related: 1F8T 1F90
• Descriptor: Fab-fragment of monoclonal antibody (3 entities in total)
• Functional Keywords: monoclonal antibody, antigen-binding fragment, interleukin-2, x-ray analysis, immune system
• Biological source: Mus musculus (house mouse); More
• Cellular location: Cell membrane ; Single-pass membrane protein : P01869
• Total number of polymer chains: 2
• Total formula weight: 48073.51

Authors

Pletnev, V.Z.,Goryacheva, E.A.,Tsygannik, I.N.,Nesmeyanov, V.A.,Pletnev, S.V.,Pangborn, W.,Duax, W. (deposition date: 2004-01-21, release date: 2004-05-25, Last modification date: 2023-08-23)

• Primary citation: Pletnev, V.Z.,Goriacheva, E.A.,Tsygannik, I.N.,Nesmeianov, V.A.,Pletnev, S.V.,Pangborn, W.,Daux, W.; [A new crystal form of the Fab fragment of a monoclonal antibody to human interleukin-2: the three-dimensional structure at 2.7 A resolution].; Bioorg. Khim., 30:466-469, ; PubMed: 15562966

Experimental method

X-RAY DIFFRACTION (2.7 Å)