1S3E
Crystal structure of MAOB in complex with 6-hydroxy-N-propargyl-1(R)-aminoindan
Summary for 1S3E
Entry DOI | 10.2210/pdb1s3e/pdb |
Related | 1S2Q 1S2Y 1S3B |
Descriptor | Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE, (3R)-3-(PROP-2-YNYLAMINO)INDAN-5-OL, ... (4 entities in total) |
Functional Keywords | human monoamine oxidase, inhibitor binding, rasagiline, enantioselectivity, flavin, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side: P27338 |
Total number of polymer chains | 2 |
Total formula weight | 119621.04 |
Authors | Binda, C.,Hubalek, F.,Li, M.,Herzig, Y.,Sterling, J.,Edmondson, D.E.,Mattevi, A. (deposition date: 2004-01-13, release date: 2004-03-30, Last modification date: 2011-07-13) |
Primary citation | Binda, C.,Li, M.,Herzig, Y.,Sterling, J.,Edmondson, D.E.,Mattevi, A. Crystal Structures of Monoamine Oxidase B in Complex with Four Inhibitors of the N-Propargylaminoindan Class. J.Med.Chem., 47:1767-1774, 2004 Cited by PubMed: 15027868DOI: 10.1021/jm031087c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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