1RQI

Active Conformation of Farnesyl Pyrophosphate Synthase Bound to Isopentyl Pyrophosphate and Dimethylallyl S-Thiolodiphosphate

Summary for 1RQI

Related1RQJ 1RTR
DescriptorGeranyltranstransferase, MAGNESIUM ION, DIMETHYLALLYL S-THIOLODIPHOSPHATE, ... (6 entities in total)
Functional Keywordsisoprenyl synthase, transferase
Biological sourceEscherichia coli
Cellular locationCytoplasm P22939
Total number of polymer chains2
Total molecular weight65881.72
Authors
Hosfield, D.J.,Zhang, Y.,Dougan, D.R.,Brooun, A.,Tari, L.W.,Swanson, R.V.,Finn, J. (deposition date: 2003-12-05, release date: 2004-03-02, Last modification date: 2011-07-13)
Primary citation
Hosfield, D.J.,Zhang, Y.,Dougan, D.R.,Brooun, A.,Tari, L.W.,Swanson, R.V.,Finn, J.
Structural basis for bisphosphonate-mediated inhibition of isoprenoid biosynthesis
J.Biol.Chem., 279:8526-8529, 2004
PubMed: 14672944 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.C300511200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.42 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers60.2%8.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1rqi
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Molmil generated image of 1rqi
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Molmil generated image of 1rqi
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