1RNC

NEWLY OBSERVED BINDING MODE IN PANCREATIC RIBONUCLEASE

1RNC の概要

• エントリーDOI: 10.2210/pdb1rnc/pdb
• 分子名称: RIBONUCLEASE A, SULFATE ION, GUANOSINE-5'-MONOPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: hydrolase(endoribonuclease)
• 由来する生物種: Bos taurus (cattle)
• 細胞内の位置: Secreted: P61823
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14167.61

構造登録者

Aguilar, C.F.,Thomas, P.J.,Mills, A.,Moss, D.S.,Palmer, R.A. (登録日: 1991-10-21, 公開日: 1994-01-31, 最終更新日: 2024-10-09)

主引用文献

Aguilar, C.F.,Thomas, P.J.,Mills, A.,Moss, D.S.,Palmer, R.A.
Newly observed binding mode in pancreatic ribonuclease.
J.Mol.Biol., 224:265-267, 1992

PubMed Abstract: Dinucleotides containing guanine, when soaked into crystals of bovine pancreatic ribonuclease, have been found to bind in an unexpected manner, quite unlike interpretations of earlier X-ray diffraction studies. This finding has prompted a reexamination of three mononucleotide-RNase complexes from this laboratory resulting in a re-interpretation of the complex that involved a guanine mononucleotide.

PubMed: 1548704
DOI: 10.1016/0022-2836(92)90589-C

実験手法

X-RAY DIFFRACTION (1.5 Å)