1RNA

CRYSTALLOGRAPHIC STRUCTURE OF AN RNA HELIX: [U(U-A)6A]2

1RNA の概要

• エントリーDOI: 10.2210/pdb1rna/pdb
• 分子名称: RNA (5'-R(*UP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*A)-3') (2 entities in total)
• 機能のキーワード: a-rna, double helix, rna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 8805.29

構造登録者

Dock-Bregeon, A.C.,Chevrier, B.,Podjarny, A.,Johnson, J.,De Bear, J.S.,Gough, G.R.,Gilham, P.T.,Moras, D. (登録日: 1990-02-01, 公開日: 1991-04-15, 最終更新日: 2024-02-14)

主引用文献

Dock-Bregeon, A.C.,Chevrier, B.,Podjarny, A.,Johnson, J.,de Bear, J.S.,Gough, G.R.,Gilham, P.T.,Moras, D.
Crystallographic structure of an RNA helix: [U(UA)6A]2.
J.Mol.Biol., 209:459-474, 1989

PubMed Abstract: The crystallographic structure of the synthetic oligoribonucleotide, U(UA)6A, has been solved at 2.25 A resolution. The crystallographic refinement permitted the identification of 91 solvent molecules, with a final agreement factor of 13%. The molecule is a dimer of 14 base-pairs and shows the typical features of an A-type helix. However, the presence of two kinks causes a divergence from a straight helix. The observed deformation, which is stabilized by a few hydrogen bonds in the crystal packing, could be due to the relatively high (35 degrees C) temperature of crystallization. The complete analysis of the structure is presented. It includes the stacking geometries, the backbone conformation and the solvation.

PubMed: 2479753
DOI: 10.1016/0022-2836(89)90010-7

実験手法

X-RAY DIFFRACTION (2.25 Å)