1RM0

Crystal Structure of Myo-Inositol 1-Phosphate Synthase From Saccharomyces cerevisiae In Complex With NAD+ and 2-deoxy-D-glucitol 6-(E)-vinylhomophosphonate

Summary for 1RM0

Entry DOI	10.2210/pdb1rm0/pdb
Descriptor	myo-inositol-phosphate synthase, MANGANESE (II) ION, (3,4,5,7-TETRAHYDROXY-HEPT-1-ENYL)-PHOSPHONIC ACID, ... (5 entities in total)
Functional Keywords	myo-inositol 1-phosphate synthase, isomerase
Biological source	Saccharomyces cerevisiae (baker's yeast)
Total number of polymer chains	2
Total formula weight	121043.52
Authors	Jin, X.,Foley, K.M.,Geiger, J.H. (deposition date: 2003-11-26, release date: 2004-05-25, Last modification date: 2024-02-14)
Primary citation	Jin, X.,Foley, K.M.,Geiger, J.H. The structure of the 1L-myo-inositol-1-phosphate synthase-NAD+-2-deoxy-D-glucitol 6-(E)-vinylhomophosphonate complex demands a revision of the enzyme mechanism. J.Biol.Chem., 279:13889-13895, 2004 Cited by PubMed: 14684747 DOI: 10.1074/jbc.M308986200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation