1RJK

crystal structure of the rat vitamin D receptor ligand binding domain complexed with 2MD and a synthetic peptide containing the NR2 box of DRIP 205

1RJK の概要

• エントリーDOI: 10.2210/pdb1rjk/pdb
• 関連するPDBエントリー: 1RK3 1RKG 1RKH
• 分子名称: Vitamin D3 receptor, Peroxisome proliferator-activated receptor binding protein, 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-2-METHYLENE-CYCLOHEXANE-1,3-DIO L, ... (4 entities in total)
• 機能のキーワード: nuclear receptor-superagonist complex, nuclear receptor-coactivator interactions, hormone-growth factor receptor complex, hormone/growth factor receptor
• 由来する生物種: Rattus norvegicus (Norway rat); 詳細
• 細胞内の位置: Nucleus: P13053 Q15648
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 34971.26

構造登録者

Vanhooke, J.L.,Benning, M.M.,Bauer, C.B.,Pike, J.W.,DeLuca, H.F. (登録日: 2003-11-19, 公開日: 2004-04-13, 最終更新日: 2023-08-23)

• 主引用文献: Vanhooke, J.L.,Benning, M.M.,Bauer, C.B.,Pike, J.W.,DeLuca, H.F.; Molecular Structure of the Rat Vitamin D Receptor Ligand Binding Domain Complexed with 2-Carbon-Substituted Vitamin D(3) Hormone Analogues and a LXXLL-Containing Coactivator Peptide; Biochemistry, 43:4101-4110, 2004; PubMed: 15065852; DOI: 10.1021/bi036056y

実験手法

X-RAY DIFFRACTION (1.99 Å)