1RII

Crystal structure of phosphoglycerate mutase from M. Tuberculosis

1RII の概要

• エントリーDOI: 10.2210/pdb1rii/pdb
• 分子名称: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, GLYCEROL (3 entities in total)
• 機能のキーワード: phosphoglyerate mutase, sh3 domain binding, structural genomics, tbsgc, protein structure initiative, psi, tb structural genomics consortium, isomerase
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 116459.18

構造登録者

Mueller, P.,Sawaya, M.R.,Chan, S.,Wu, Y.,Pashkova, I.,Perry, J.,Eisenberg, D.,TB Structural Genomics Consortium (TBSGC) (登録日: 2003-11-17, 公開日: 2004-10-05, 最終更新日: 2023-08-23)

主引用文献

Muller, P.,Sawaya, M.R.,Pashkov, I.,Chan, S.,Nguyen, C.,Wu, Y.,Perry, L.J.,Eisenberg, D.
The 1.70 angstroms X-ray crystal structure of Mycobacterium tuberculosis phosphoglycerate mutase.
Acta Crystallogr.,Sect.D, 61:309-315, 2005

PubMed Abstract: The single-crystal X-ray structure of phosphoglycerate mutase from Mycobacterium tuberculosis has been determined at a resolution of 1.70 angstroms. The C-terminal tail of each of the subunits is flexible and disordered; however, for one of the four chains (chain A) all but five residues of the chain could be modeled. Noteworthy features of the structure include the active site and a proline-rich segment in each monomer forming a short left-handed polyprolyl helix. These segments lie on the enzyme surface and could conceivably participate in protein-protein interactions.

PubMed: 15735341
DOI: 10.1107/S0907444904033190

実験手法

X-RAY DIFFRACTION (1.7 Å)