1RER

Crystal structure of the homotrimer of fusion glycoprotein E1 from Semliki Forest Virus.

Summary for 1RER

• Entry DOI: 10.2210/pdb1rer/pdb
• Related: 1I9W
• Descriptor: Structural polyprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: envelope glycoprotein, membrane fusion, virus., viral protein
• Biological source: Semliki forest virus
• Cellular location: Capsid protein: Virion . p62: Virion membrane ; Single- pass type I membrane protein . Envelope glycoprotein E2: Virion membrane ; Single-pass type I membrane protein . Envelope glycoprotein E1: Virion membrane ; Single-pass type I membrane protein . Protein 6K: Host cell membrane ; Multi-pass membrane protein : P03315
• Total number of polymer chains: 3
• Total formula weight: 131847.35

Authors

Gibbons, D.L.,Vaney, M.C.,Roussel, A.,Vigouroux, A.,Reilly, B.,Kielian, M.,Rey, F.A. (deposition date: 2003-11-07, release date: 2004-01-27, Last modification date: 2020-07-29)

• Primary citation: Gibbons, D.L.,Vaney, M.C.,Roussel, A.,Vigouroux, A.,Reilly, B.,Lepault, J.,Kielian, M.,Rey, F.A.; Conformational change and protein-protein interactions of the fusion protein of Semliki Forest virus.; Nature, 427:320-325, 2004; PubMed: 14737160; DOI: 10.1038/nature02239

Experimental method

X-RAY DIFFRACTION (3.2 Å)