1RER

Crystal structure of the homotrimer of fusion glycoprotein E1 from Semliki Forest Virus.

1RER の概要

• エントリーDOI: 10.2210/pdb1rer/pdb
• 関連するPDBエントリー: 1I9W
• 分子名称: Structural polyprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: envelope glycoprotein, membrane fusion, virus., viral protein
• 由来する生物種: Semliki forest virus
• 細胞内の位置: Capsid protein: Virion . p62: Virion membrane ; Single- pass type I membrane protein . Envelope glycoprotein E2: Virion membrane ; Single-pass type I membrane protein . Envelope glycoprotein E1: Virion membrane ; Single-pass type I membrane protein . Protein 6K: Host cell membrane ; Multi-pass membrane protein : P03315
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 131847.35

構造登録者

Gibbons, D.L.,Vaney, M.C.,Roussel, A.,Vigouroux, A.,Reilly, B.,Kielian, M.,Rey, F.A. (登録日: 2003-11-07, 公開日: 2004-01-27, 最終更新日: 2020-07-29)

• 主引用文献: Gibbons, D.L.,Vaney, M.C.,Roussel, A.,Vigouroux, A.,Reilly, B.,Lepault, J.,Kielian, M.,Rey, F.A.; Conformational change and protein-protein interactions of the fusion protein of Semliki Forest virus.; Nature, 427:320-325, 2004; PubMed: 14737160; DOI: 10.1038/nature02239

実験手法

X-RAY DIFFRACTION (3.2 Å)