1RDQ

Hydrolysis of ATP in the crystal of Y204A mutant of cAMP-dependent protein kinase

1RDQ の概要

• エントリーDOI: 10.2210/pdb1rdq/pdb
• 関連するPDBエントリー: 1ATP
• 分子名称: cAMP-dependent protein kinase, alpha-catalytic subunit, cAMP-dependent protein kinase inhibitor, alpha form, PHOSPHATE ION, ... (9 entities in total)
• 機能のキーワード: camp-dependent protein kinase, catalytic mechanism, atp hydrolysis, two nucleotide states, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Mus musculus (house mouse); 詳細
• 細胞内の位置: Cytoplasm . Isoform 2: Cell projection, cilium, flagellum : P05132
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 44079.86

構造登録者

Yang, J.,Ten Eyck, L.F.,Xuong, N.H.,Taylor, S.S. (登録日: 2003-11-05, 公開日: 2004-04-13, 最終更新日: 2023-08-23)

• 主引用文献: Yang, J.,Ten Eyck, L.F.,Xuong, N.H.,Taylor, S.S.; Crystal Structure of a cAMP-dependent Protein Kinase Mutant at 1.26A: New Insights into the Catalytic Mechanism.; J.Mol.Biol., 336:473-487, 2004; PubMed: 14757059; DOI: 10.1016/j.jmb.2003.11.044

実験手法

X-RAY DIFFRACTION (1.26 Å)