1R20

Crystal structure of the ligand-binding domains of the heterodimer EcR/USP bound to the synthetic agonist BYI06830

1R20 の概要

• エントリーDOI: 10.2210/pdb1r20/pdb
• 関連するPDBエントリー: 1R1K
• 分子名称: ULTRASPIRACLE PROTEIN, ECDYSONE RECEPTOR, L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE, ... (5 entities in total)
• 機能のキーワード: nuclear receptor, heterodimer, alpha-helical sandwich, structural proteomics in europe, spine, structural genomics, hormone-growth factor receptor complex, hormone/growth factor receptor
• 由来する生物種: Heliothis virescens (tobacco budworm); 詳細
• 細胞内の位置: Nucleus: O18473
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 61264.79

構造登録者

Billas, I.M.L.,Iwema, T.,Garnier, J.M.,Mitschler, A.,Rochel, N.,Moras, D.,Structural Proteomics in Europe (SPINE) (登録日: 2003-09-25, 公開日: 2003-11-18, 最終更新日: 2024-02-14)

• 主引用文献: Billas, I.M.L.,Iwema, T.,Garnier, J.M.,Mitschler, A.,Rochel, N.,Moras, D.; Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor.; Nature, 426:91-96, 2003; PubMed: 14595375; DOI: 10.1038/nature02112

実験手法

X-RAY DIFFRACTION (3 Å)