1R1L
Structure of dimeric antithrombin complexed with a P14-P9 reactive loop peptide and an exogenous tripeptide (formyl-norleucine-LF)
Summary for 1R1L
Entry DOI | 10.2210/pdb1r1l/pdb |
Related | 1JVQ 1LK6 |
Descriptor | Antithrombin-III, Antithrombin P14-P9 peptide, EXOGENOUS TRIPEPTIDE formyl-(NLE)LF, ... (7 entities in total) |
Functional Keywords | serpin, loop-sheet polymer, beta-barrel, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P01008 |
Total number of polymer chains | 4 |
Total formula weight | 100824.67 |
Authors | Zhou, A.,Huntington, J.A.,Lomas, D.A.,Stein, P.E.,Carrell, R.W. (deposition date: 2003-09-24, release date: 2004-10-05, Last modification date: 2023-11-15) |
Primary citation | Zhou, A.,Huntington, J.A.,Lomas, D.A.,Stein, P.E.,Carrell, R.W. Serpins and the design of peptides to block intermolecular beta-linkages To be Published, |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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