1QUV
CRYSTAL STRUCTURE OF THE RNA DIRECTED RNA POLYMERASE OF HEPATITIS C VIRUS
Summary for 1QUV
Entry DOI | 10.2210/pdb1quv/pdb |
Descriptor | PROTEIN (RNA-DIRECTED RNA POLYMERASE) (2 entities in total) |
Functional Keywords | rna dependent rna polymerase, replicase, hcv, ns5b, transferase |
Biological source | Hepatitis C virus |
Cellular location | Core protein p21: Host endoplasmic reticulum membrane; Single-pass membrane protein. Core protein p19: Virion . Envelope glycoprotein E1: Virion membrane ; Single-pass type I membrane protein . Envelope glycoprotein E2: Virion membrane ; Single-pass type I membrane protein . p7: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Protease NS2-3: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Serine protease NS3: Host endoplasmic reticulum membrane ; Peripheral membrane protein . Non-structural protein 4A: Host endoplasmic reticulum membrane ; Single-pass type I membrane protein . Non-structural protein 4B: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Non-structural protein 5A: Host endoplasmic reticulum membrane ; Peripheral membrane protein . RNA-directed RNA polymerase: Host endoplasmic reticulum membrane ; Single-pass type I membrane protein : P26663 |
Total number of polymer chains | 1 |
Total formula weight | 64247.60 |
Authors | Ago, H.,Miyano, M.,Adachi, T.,Habuka, N. (deposition date: 1999-07-04, release date: 1999-11-05, Last modification date: 2024-02-14) |
Primary citation | Ago, H.,Adachi, T.,Yoshida, A.,Yamamoto, M.,Habuka, N.,Yatsunami, K.,Miyano, M. Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus. Structure Fold.Des., 7:1417-1426, 1999 Cited by PubMed: 10574802DOI: 10.1016/S0969-2126(00)80031-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report