1QSX
SOLUTION NMR STRUCTURE OF THE 2:1 HOECHST 33258-D(CTTTTGCAAAAG)2 COMPLEX
Summary for 1QSX
Entry DOI | 10.2210/pdb1qsx/pdb |
Descriptor | 5'-D(CP*TP*TP*TP*TP*GP*CP*AP*AP*AP*AP*G)-3', SODIUM ION, 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE (3 entities in total) |
Functional Keywords | drug-dna complex, hoechst 33258, deoxyribonucleic acid, minor groove recognition, double helix, nmr spectroscopy, dna |
Total number of polymer chains | 2 |
Total formula weight | 8608.64 |
Authors | Gavathiotis, E.,Sharman, G.J.,Searle, M.S. (deposition date: 1999-06-24, release date: 2000-02-07, Last modification date: 2024-05-22) |
Primary citation | Gavathiotis, E.,Sharman, G.J.,Searle, M.S. Sequence-dependent variation in DNA minor groove width dictates orientational preference of Hoechst 33258 in A-tract recognition: solution NMR structure of the 2:1 complex with d(CTTTTGCAAAAG)(2). Nucleic Acids Res., 28:728-735, 2000 Cited by PubMed: 10637324DOI: 10.1093/nar/28.3.728 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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