1QSX

SOLUTION NMR STRUCTURE OF THE 2:1 HOECHST 33258-D(CTTTTGCAAAAG)2 COMPLEX

1QSX の概要

• エントリーDOI: 10.2210/pdb1qsx/pdb
• 分子名称: 5'-D(CP*TP*TP*TP*TP*GP*CP*AP*AP*AP*AP*G)-3', SODIUM ION, 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE (3 entities in total)
• 機能のキーワード: drug-dna complex, hoechst 33258, deoxyribonucleic acid, minor groove recognition, double helix, nmr spectroscopy, dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 8608.64

構造登録者

Gavathiotis, E.,Sharman, G.J.,Searle, M.S. (登録日: 1999-06-24, 公開日: 2000-02-07, 最終更新日: 2022-03-02)

• 主引用文献: Gavathiotis, E.,Sharman, G.J.,Searle, M.S.; Sequence-dependent variation in DNA minor groove width dictates orientational preference of Hoechst 33258 in A-tract recognition: solution NMR structure of the 2:1 complex with d(CTTTTGCAAAAG)(2).; Nucleic Acids Res., 28:728-735, 2000; PubMed: 10637324; DOI: 10.1093/nar/28.3.728

実験手法

SOLUTION NMR