1QQQ

CRYSTAL STRUCTURE ANALYSIS OF SER254 MUTANT OF ESCHERICHIA COLI THYMIDYLATE SYNTHASE

Summary for 1QQQ

• Entry DOI: 10.2210/pdb1qqq/pdb
• Descriptor: THYMIDYLATE SYNTHASE, SULFATE ION (3 entities in total)
• Functional Keywords: thymidylate synthase, methyltransferase, transferase
• Biological source: Escherichia coli
• Cellular location: Cytoplasm: P0A884
• Total number of polymer chains: 1
• Total formula weight: 31142.28

Authors

Fantz, C.,Shaw, D.,Jennings, W.,Forsthoefel, A.,Kitchens, M.,Phan, J.,Minor, W.,Lebioda, L.,Berger, F.G.,Spencer, H.T. (deposition date: 1999-06-07, release date: 1999-06-14, Last modification date: 2022-04-13)

• Primary citation: Fantz, C.,Shaw, D.,Jennings, W.,Forsthoefel, A.,Kitchens, M.,Phan, J.,Minor, W.,Lebioda, L.,Berger, F.G.,Spencer, H.T.; Drug-resistant variants of Escherichia coli thymidylate synthase: effects of substitutions at Pro-254.; Mol.Pharmacol., 57:359-366, 2000; PubMed: 10648646

Experimental method

X-RAY DIFFRACTION (1.5 Å)