1QPR

QUINOLINATE PHOSPHORIBOSYLTRANSFERASE (QAPRTASE) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH PHTHALATE AND PRPCP

1QPR の概要

• エントリーDOI: 10.2210/pdb1qpr/pdb
• 分子名称: QUINOLINIC ACID PHOSPHORIBOSYLTRANSFERASE, MANGANESE (II) ION, PHTHALIC ACID, ... (5 entities in total)
• 機能のキーワード: prtase, de novo nad biosynthesis, prpp, transferase, phosphoribosyltransferase, quinolinic acid, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc
• 由来する生物種: Mycobacterium tuberculosis H37Rv
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 183089.80

構造登録者

Sharma, V.,Grubmeyer, C.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (登録日: 1998-10-17, 公開日: 1998-10-21, 最終更新日: 2024-02-14)

• 主引用文献: Sharma, V.,Grubmeyer, C.,Sacchettini, J.C.; Crystal structure of quinolinic acid phosphoribosyltransferase from Mycobacterium tuberculosis: a potential TB drug target.; Structure, 6:1587-1599, 1998; PubMed: 9862811; DOI: 10.1016/S0969-2126(98)00156-7

実験手法

X-RAY DIFFRACTION (2.45 Å)