1QMY

FMDV LEADER PROTEASE (LBSHORT-C51A-C133S)

Summary for 1QMY

Related1QOL 1QQP
DescriptorPROTEASE, 1,2-ETHANEDIOL (3 entities in total)
Functional Keywordshydrolase, sulfhydryl proteinase, picornaviral proteinase
Biological sourceAPHTHOVIRUS O (FOOT-AND-MOUTH DISEASE VIRUS, FMDV)
Cellular locationProtein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B-1: Virion (Potential). Protein 3B-2: Virion (Potential). Protein 3B-3: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential) P03305
Total number of polymer chains3
Total molecular weight57145.68
Authors
Guarne, A.,Tormo, J.,Glaser, W.,Skern, T.,Fita, I. (deposition date: 1999-10-08, release date: 2000-10-12, Last modification date: 2011-07-13)
Primary citation
Guarne, A.,Hampoelz, B.,Glaser, W.,Carpena, X.,Tormo, J.,Fita, I.,Skern, T.
Structure and Biochemical Features Distinguish the Foot-and-Mouth Disease Virus Leader Proteinase from Other Papain-Like Enzymes
J.Mol.Biol., 302:1227-, 2000
PubMed: 11183785 (PDB entries with the same primary citation)
DOI: 10.1006/JMBI.2000.4115
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23160.9%2.5%1.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution