1QMS

Head-to-Tail Dimer of Calicheamicin gamma-1-I Oligosaccharide Bound to DNA Duplex, NMR, 9 Structures

1QMS の概要

• エントリーDOI: 10.2210/pdb1qms/pdb
• 分子名称: DNA (5'-D(*GP*CP*AP*CP*CP*TP*TP*CP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*GP*GP*AP*AP*GP*GP*TP*GP*C)-3'), CALICHEAMICIN GAMMA-1-OLIGOSACCHARIDE, ... (4 entities in total)
• 機能のキーワード: deoxyribonucleic acid/calicheamicin, calicheamicin, head-to-tail dimer, dna, minor groove binding, antitumor agent, ligand-dna complex, deoxyribonucleic acid
• 由来する生物種: synthetic construct; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 9338.63

構造登録者

Bifulco, G.,Galeone, A.,Nicolaou, K.C.,Chazin, W.J.,Gomez-Paloma, L. (登録日: 1999-10-06, 公開日: 1999-10-12, 最終更新日: 2024-05-15)

• 主引用文献: Bifulco, G.,Galeone, A.,Nicolaou, K.C.,Chazin, W.J.,Gomez-Paloma, L.; Solution Structure of the Complex between the Head-to-Tail Dimer of Calicheamicin Gamma-1-I Oligosaccharide and a DNA Duplex Containing D(ACCT) and D(TCCT) High-Affinity Binding Sites; J.Am.Chem.Soc., 120:7183-7191, 1998; DOI: 10.1021/ja973910y

実験手法

SOLUTION NMR