1QJH

Protein Aggregation and Alzheimer's Disease: Crystallographic Analysis of the Phenomenon. Engineered version of the ribosomal protein S6 used as a stable scaffold to study oligomerization.

1QJH の概要

• エントリーDOI: 10.2210/pdb1qjh/pdb
• 関連するPDBエントリー: 1CQM 1CQN 1LOU 1RIS
• 分子名称: 30S ribosomal protein S6, MAGNESIUM ION (3 entities in total)
• 機能のキーワード: ribosomal protein, alzheimer disease, ribosomal protein s6, oligomerization
• 由来する生物種: Thermus thermophilus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 11855.01

構造登録者

Kristensen, O.,Otzen, D.E.,Oliveberg, M. (登録日: 1999-06-24, 公開日: 2000-06-29, 最終更新日: 2023-12-13)

• 主引用文献: Otzen, D.E.,Kristensen, O.,Oliveberg, M.; Designed protein tetramer zipped together with a hydrophobic Alzheimer homology: a structural clue to amyloid assembly.; Proc. Natl. Acad. Sci. U.S.A., 97:9907-9912, 2000; PubMed: 10944185; DOI: 10.1073/pnas.160086297

実験手法

X-RAY DIFFRACTION (2.2 Å)