1QIQ

ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (ACmC Fe COMPLEX)

1QIQ の概要

• エントリーDOI: 10.2210/pdb1qiq/pdb
• 分子名称: ISOPENICILLIN N SYNTHASE, N-[N-[2-AMINO-6-OXO-HEXANOIC ACID-6-YL]CYSTEINYL]-S-METHYLCYSTEINE, FE (III) ION, ... (5 entities in total)
• 機能のキーワード: antibiotic biosynthesis, b-lactam antibiotic, monocyclic intermediate, oxygenase, penicillin biosynthesis
• 由来する生物種: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 38098.22

構造登録者

Rutledge, P.J.,Clifton, I.J.,Burzlaff, N.I.,Roach, P.L.,Adlington, R.M.,Baldwin, J.E. (登録日: 1999-06-15, 公開日: 2000-06-16, 最終更新日: 2024-05-08)

• 主引用文献: Burzlaff, N.I.,Rutledge, P.J.,Clifton, I.J.,Hensgens, C.M.H.,Pickford, M.,Adlington, R.M.,Roach, P.L.,Baldwin, J.E.; The Reaction Cycle of Isopenicillin N Synthase Observed by X-Ray Diffraction.; Nature, 401:721-, 1999; PubMed: 10537113; DOI: 10.1038/44400

実験手法

X-RAY DIFFRACTION (1.5 Å)