1QIP

HUMAN GLYOXALASE I COMPLEXED WITH S-P-NITROBENZYLOXYCARBONYLGLUTATHIONE

Summary for 1QIP

Related1QIN
DescriptorPROTEIN (LACTOYLGLUTATHIONE LYASE), ZINC ION, S-P-NITROBENZYLOXYCARBONYLGLUTATHIONE, ... (5 entities in total)
Functional Keywordslyase, lactoylglutathione lyase, glyoxalase i
Biological sourceHomo sapiens (human)
Total number of polymer chains4
Total molecular weight85218.12
Authors
Cameron, A.D.,Ridderstrom, M.,Olin, B.,Mannervik, B. (deposition date: 1999-06-14, release date: 1999-11-24, Last modification date: 2011-07-13)
Primary citation
Cameron, A.D.,Ridderstrom, M.,Olin, B.,Kavarana, M.J.,Creighton, D.J.,Mannervik, B.
Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue.
Biochemistry, 38:13480-13490, 1999
PubMed: 10521255 (PDB entries with the same primary citation)
DOI: 10.1021/bi990696c
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.72 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers40.1%2.7%3.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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Molmil generated image of 1qip
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More Biological unit images

Molmil generated image of 1qip
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Molmil generated image of 1qip
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Molmil generated image of 1qip
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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (1qip.pdb1.gz [71.17 KB])
Coordinate files for Biological unit (1qip.pdb2.gz [70.57 KB])