1QIN

HUMAN GLYOXALASE I COMPLEXED WITH S-(N-HYDROXY-N-P-IODOPHENYLCARBAMOYL) GLUTATHIONE

Summary for 1QIN

Related1QIP
DescriptorPROTEIN (LACTOYLGLUTATHIONE LYASE), ZINC ION, S-(N-HYDROXY-N-IODOPHENYLCARBAMOYL)GLUTATHIONE, ... (4 entities in total)
Functional Keywordslyase, lactoylglutathione lyase, glyoxalase i
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight42616.57
Authors
Cameron, A.D.,Ridderstrom, M.,Olin, B.,Mannervik, B. (deposition date: 1999-06-14, release date: 1999-11-24, Last modification date: 2011-07-13)
Primary citation
Cameron, A.D.,Ridderstrom, M.,Olin, B.,Kavarana, M.J.,Creighton, D.J.,Mannervik, B.
Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue.
Biochemistry, 38:13480-13490, 1999
PubMed: 10521255 (PDB entries with the same primary citation)
DOI: 10.1021/bi990696c
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers200.7%2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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