1QIA

CRYSTAL STRUCTURE OF STROMELYSIN CATALYTIC DOMAIN

1QIA の概要

• エントリーDOI: 10.2210/pdb1qia/pdb
• 分子名称: STROMELYSIN-1, ZINC ION, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: inhibitor, matrixin, matrix metalloproteinase-3 (mmp-3), stromelysin-1, metzincin, hydrolase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted, extracellular space, extracellular matrix : P08254
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 73725.08

構造登録者

Williams, M.G.,Ye, Q.-Z.,Molina, F.,Johnson, L.L.,Ortwine, D.F.,Pavlovsky, A.G.,Rubin, J.R.,Skeean, R.W.,White, A.D.,Blundell, T.L.,Humblet, C.,Hupe, D.J.,Dhanaraj, V. (登録日: 1999-06-11, 公開日: 2003-02-11, 最終更新日: 2023-12-27)

• 主引用文献: Pavlovsky, A.G.,Williams, M.G.,Ye, Q.-Z.,Ortwine, D.F.,Purchase II, C.F.,White, A.D.,Dhanaraj, V.,Roth, B.D.,Johnson, L.L.,Hupe, D.J.,Humblet, C.,Blundell, T.L.; X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity; Protein Sci., 8:1455-1462, 1999; PubMed: 10422833

実験手法

X-RAY DIFFRACTION (2 Å)