1QG1
GROWTH FACTOR RECEPTOR BINDING PROTEIN SH2 DOMAIN COMPLEXED WITH AN SHC-DERIVED PEPTIDE
Summary for 1QG1
Entry DOI | 10.2210/pdb1qg1/pdb |
Descriptor | PROTEIN (GROWTH FACTOR RECEPTOR BINDING PROTEIN), PROTEIN (SHC-DERIVED PEPTIDE) (2 entities in total) |
Functional Keywords | signal transduction, sh2 domain, phosphotyrosyl peptide, complex (signal transduction-peptide), hormone-growth factor complex, hormone/growth factor |
Biological source | Homo sapiens (human) More |
Cellular location | Golgi apparatus (By similarity): P62993 Cytoplasm. Isoform p46Shc: Mitochondrion matrix. Isoform p66Shc: Mitochondrion (By similarity): P29353 |
Total number of polymer chains | 2 |
Total formula weight | 13600.07 |
Authors | Ogura, K. (deposition date: 1999-04-19, release date: 1999-04-27, Last modification date: 2023-12-27) |
Primary citation | Ogura, K.,Tsuchiya, S.,Terasawa, H.,Yuzawa, S.,Hatanaka, H.,Mandiyan, V.,Schlessinger, J.,Inagaki, F. Solution structure of the SH2 domain of Grb2 complexed with the Shc-derived phosphotyrosine-containing peptide. J.Mol.Biol., 289:439-445, 1999 Cited by PubMed: 10356320DOI: 10.1006/jmbi.1999.2792 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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