1QB9
BOVINE TRYPSIN 7-[[2-[[1-(1-IMINOETHYL)PIPERIDIN-4-YL]OXY]-9H-CARBOZOL-9-YL] METHYL]NAPHTHALENE-2-CARBOXIMIDAMIDE (ZK-806450) COMPLEX
Summary for 1QB9
Entry DOI | 10.2210/pdb1qb9/pdb |
Descriptor | PROTEIN (TRYPSIN), CALCIUM ION, POTASSIUM ION, ... (5 entities in total) |
Functional Keywords | hydrolase, serine proteinase, protein-inhibitor complex, s1 pocket, factor xa |
Biological source | Bos taurus (cattle) |
Cellular location | Secreted, extracellular space: P00760 |
Total number of polymer chains | 1 |
Total formula weight | 23933.15 |
Authors | Whitlow, M. (deposition date: 1999-04-30, release date: 2000-04-30, Last modification date: 2014-03-12) |
Primary citation | Whitlow, M.,Arnaiz, D.O.,Buckman, B.O.,Davey, D.D.,Griedel, B.,Guilford, W.J.,Koovakkat, S.K.,Liang, A.,Mohan, R.,Phillips, G.B.,Seto, M.,Shaw, K.J.,Xu, W.,Zhao, Z.,Light, D.R.,Morrissey, M.M. Crystallographic analysis of potent and selective factor Xa inhibitors complexed to bovine trypsin. Acta Crystallogr.,Sect.D, 55:1395-1404, 1999 Cited by PubMed: 10417407DOI: 10.1107/S0907444999007350 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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