1Q0R
Crystal structure of aclacinomycin methylesterase (RdmC) with bound product analogue, 10-decarboxymethylaclacinomycin T (DcmaT)
Summary for 1Q0R
| Entry DOI | 10.2210/pdb1q0r/pdb |
| Related | 1Q0Z |
| Descriptor | aclacinomycin methylesterase, 10-DECARBOXYMETHYLACLACINOMYCIN T (DCMAT), SULFATE ION, ... (5 entities in total) |
| Functional Keywords | anthracycline, methylesterase, hydrolase, polyketide, streptomyces, tailoring enzyme, structural proteomics in europe, spine, structural genomics |
| Biological source | Streptomyces purpurascens |
| Total number of polymer chains | 1 |
| Total formula weight | 32674.78 |
| Authors | Jansson, A.,Niemi, J.,Mantsala, P.,Schneider, G.,Structural Proteomics in Europe (SPINE) (deposition date: 2003-07-17, release date: 2003-11-25, Last modification date: 2024-02-14) |
| Primary citation | Jansson, A.,Niemi, J.,Mantsala, P.,Schneider, G. Crystal structure of aclacinomycin methylesterase with bound product analogues: implications for anthracycline recognition and mechanism. J.Biol.Chem., 278:39006-39013, 2003 Cited by PubMed: 12878604DOI: 10.1074/jbc.M304008200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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