1PZU

An asymmetric NFAT1-RHR homodimer on a pseudo-palindromic, Kappa-B site

Summary for 1PZU

• Entry DOI: 10.2210/pdb1pzu/pdb
• Related: 1A02
• Descriptor: 5'-D(*TP*TP*GP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*A)-3', 5'-D(*AP*AP*TP*GP*GP*AP*AP*AP*TP*TP*CP*CP*TP*C)-3', Nuclear factor of activated T-cells, cytoplasmic 2 (3 entities in total)
• Functional Keywords: transcription factor, nfat1-rhr homodimer, protein-dna complex, human il8 promoter, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q13469
• Total number of polymer chains: 12
• Total formula weight: 231301.24

Authors

Jin, L.,Sliz, P.,Chen, L.,Macian, F.,Rao, A.,Hogan, P.G.,Harrison, S.C. (deposition date: 2003-07-14, release date: 2003-09-09, Last modification date: 2024-02-21)

• Primary citation: Jin, L.,Sliz, P.,Chen, L.,Macian, F.,Rao, A.,Hogan, P.G.,Harrison, S.C.; An asymmetric NFAT1 dimer on a pseudo-palindromic KB-like DNA site; Nat.Struct.Biol., 10:807-811, 2003; PubMed: 12949491; DOI: 10.1038/nsb975

Experimental method

X-RAY DIFFRACTION (3.1 Å)