1PZK
Cholera Toxin B-Pentamer Complexed With N-Acyl Phenyl Galactoside 9h
Summary for 1PZK
Entry DOI | 10.2210/pdb1pzk/pdb |
Related | 1PZI 1PZJ |
Descriptor | Cholera Toxin B Subunit, N-{3-[4-(3-AMINO-PROPYL)-PIPERAZIN-1-YL]-PROPYL}-3-(2-THIOPHEN-2-YL-ACETYLAMINO)-5-(3,4,5-TRIHYDROXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-2-YLOXY)-BENZAMIDE (3 entities in total) |
Functional Keywords | pentamer, monovalent, toxin, inhibitor, cholera |
Biological source | Vibrio cholerae |
Total number of polymer chains | 5 |
Total formula weight | 61225.06 |
Authors | Mitchell, D.D.,Pickens, J.C.,Korotkov, K.,Fan, E.,Hol, W.G.J. (deposition date: 2003-07-11, release date: 2004-03-09, Last modification date: 2023-08-16) |
Primary citation | Mitchell, D.D.,Pickens, J.C.,Korotkov, K.,Fan, E.,Hol, W.G.J. 3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies Bioorg.Med.Chem., 12:907-920, 2004 Cited by PubMed: 14980603DOI: 10.1016/j.bmc.2003.12.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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