1PZI

Heat-Labile Enterotoxin B-Pentamer Complexed With Nitrophenyl Galactoside 2a

Summary for 1PZI

• Entry DOI: 10.2210/pdb1pzi/pdb
• Related: 1PZJ 1PZK
• Descriptor: Heat-labile Enterotoxin B subunit, N-(2-MORPHOLIN-4-YL-1-MORPHOLIN-4-YLMETHYL-ETHYL)-3-NITRO-5-(3,4,5-TRIHYDROXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-2-YLOXY)-BENZAMIDE (3 entities in total)
• Functional Keywords: pentamer, monovalent, toxin, inhibitor, toxin inhibitor
• Biological source: Escherichia coli
• Total number of polymer chains: 5
• Total formula weight: 61820.51

Authors

Mitchell, D.D.,Pickens, J.C.,Korotkov, K.,Fan, E.,Hol, W.G.J. (deposition date: 2003-07-11, release date: 2004-03-09, Last modification date: 2023-08-16)

• Primary citation: Mitchell, D.D.,Pickens, J.C.,Korotkov, K.,Fan, E.,Hol, W.G.J.; 3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies; Bioorg.Med.Chem., 12:907-920, 2004; PubMed: 14980603; DOI: 10.1016/j.bmc.2003.12.019

Experimental method

X-RAY DIFFRACTION (1.99 Å)