1PZI

Heat-Labile Enterotoxin B-Pentamer Complexed With Nitrophenyl Galactoside 2a

1PZI の概要

• エントリーDOI: 10.2210/pdb1pzi/pdb
• 関連するPDBエントリー: 1PZJ 1PZK
• 分子名称: Heat-labile Enterotoxin B subunit, N-(2-MORPHOLIN-4-YL-1-MORPHOLIN-4-YLMETHYL-ETHYL)-3-NITRO-5-(3,4,5-TRIHYDROXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-2-YLOXY)-BENZAMIDE (3 entities in total)
• 機能のキーワード: pentamer, monovalent, toxin, inhibitor, toxin inhibitor
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 61820.51

構造登録者

Mitchell, D.D.,Pickens, J.C.,Korotkov, K.,Fan, E.,Hol, W.G.J. (登録日: 2003-07-11, 公開日: 2004-03-09, 最終更新日: 2023-08-16)

• 主引用文献: Mitchell, D.D.,Pickens, J.C.,Korotkov, K.,Fan, E.,Hol, W.G.J.; 3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies; Bioorg.Med.Chem., 12:907-920, 2004; PubMed: 14980603; DOI: 10.1016/j.bmc.2003.12.019

実験手法

X-RAY DIFFRACTION (1.99 Å)