1PYX

GSK-3 Beta complexed with AMP-PNP

1PYX の概要

分子名称Glycogen synthase kinase-3 beta, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total)
機能のキーワードkinase, insulin pathway, transferase
由来する生物種Homo sapiens (human)
細胞内の位置Cytoplasm P49841
ポリマー鎖数2
分子量合計95020.38
構造登録者
Bertrand, J.A.,Thieffine, S.,Vulpetti, A.,Cristiani, C.,Valsasina, B.,Knapp, S.,Kalisz, H.M.,Flocco, M. (登録日: 2003-07-09, 公開日: 2003-10-21, 最終更新日: 2011-07-13)
主引用文献
Bertrand, J.A.,Thieffine, S.,Vulpetti, A.,Cristiani, C.,Valsasina, B.,Knapp, S.,Kalisz, H.M.,Flocco, M.
Structural characterization of the GSK-3beta active site using selective and non-selective ATP-mimetic inhibitors
J.Mol.Biol., 333:393-407, 2003
PubMed: 14529625 (主引用文献が同じPDBエントリー)
DOI: 10.1016/j.jmb.2003.08.031
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.4 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23090.9%4.6%8.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード