1PUP

CRYSTAL STRUCTURE OF A PEPTIDE NUCLEIC ACID (PNA) DUPLEX AT 1.7 ANGSTROMS RESOLUTION

1PUP の概要

• エントリーDOI: 10.2210/pdb1pup/pdb
• 分子名称: PNA (H-P(*CPN*GPN*TPN*APN*CPN*GPN)-NH2) (2 entities in total)
• 機能のキーワード: peptide nucleic acid, dna analogue, double helix
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 3171.27

構造登録者

Rasmussen, H.,Kastrup, J.S. (登録日: 1996-11-01, 公開日: 1997-02-25, 最終更新日: 2023-11-15)

主引用文献

Rasmussen, H.,Kastrup, J.S.,Nielsen, J.N.,Nielsen, J.M.,Nielsen, P.E.
Crystal structure of a peptide nucleic acid (PNA) duplex at 1.7 A resolution.
Nat.Struct.Biol., 4:98-101, 1997

PubMed Abstract: The crystal structure of a PNA duplex reveals both a right- and a left-handed helix in the unit cell. The helices are wide (28A), large pitched (18bp) with the base pairs perpendicular to the helix axis, thereby demonstrating that PNA besides adapting to oligonucleotide partners also has a unique structure by itself.

PubMed: 9033585
DOI: 10.1038/nsb0297-98

実験手法

X-RAY DIFFRACTION (1.7 Å)