1PTV

CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH PHOSPHOTYROSINE

Summary for 1PTV

Entry DOI	10.2210/pdb1ptv/pdb
Descriptor	PROTEIN TYROSINE PHOSPHATASE 1B, O-PHOSPHOTYROSINE (3 entities in total)
Functional Keywords	hydrolase, acetylation, phosphorylation, complex (hydrolase-peptide) complex, complex (hydrolase/peptide)
Biological source	Homo sapiens (human)
Cellular location	Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side: P18031
Total number of polymer chains	1
Total formula weight	37610.74
Authors	Barford, D.,Jia, Z. (deposition date: 1995-04-21, release date: 1996-08-01, Last modification date: 2024-02-14)
Primary citation	Jia, Z.,Barford, D.,Flint, A.J.,Tonks, N.K. Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B. Science, 268:1754-1758, 1995 Cited by PubMed: 7540771 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation