1PSZ

PNEUMOCOCCAL SURFACE ANTIGEN PSAA

Summary for 1PSZ

• Entry DOI: 10.2210/pdb1psz/pdb
• Descriptor: PROTEIN (SURFACE ANTIGEN PSAA), ZINC ION (3 entities in total)
• Functional Keywords: psaa, abc-type binding protein, metal-binding protein, pneumococcal surface antigen, immune system
• Biological source: Streptococcus pneumoniae
• Cellular location: Cell membrane ; Lipid-anchor : P0A4G2
• Total number of polymer chains: 1
• Total formula weight: 34208.66

Authors

Lawrence, M.C.,Pilling, P.A.,Epa, V.C.,Berry, A.M.,Ogunniyi, A.D.,Paton, J.C. (deposition date: 1998-10-13, release date: 2000-04-19, Last modification date: 2023-12-27)

Primary citation

Lawrence, M.C.,Pilling, P.A.,Epa, V.C.,Berry, A.M.,Ogunniyi, A.D.,Paton, J.C.
The crystal structure of pneumococcal surface antigen PsaA reveals a metal-binding site and a novel structure for a putative ABC-type binding protein.
Structure, 6:1553-1561, 1998

PubMed Abstract: . The surface protein PsaA of the pathogenic bacterium Streptococcus pneumoniae plays an essential role in its virulence. PsaA is a putative ATP-binding cassette-type (ABC-type) binding protein involved in the uptake of Mn2+ and possibly Zn2+ and is considered to be both a potential drug target and and a candidate vaccine component.

PubMed: 9862808
DOI: 10.1016/S0969-2126(98)00153-1

Experimental method

X-RAY DIFFRACTION (2 Å)