1PSZ

PNEUMOCOCCAL SURFACE ANTIGEN PSAA

1PSZ の概要

• エントリーDOI: 10.2210/pdb1psz/pdb
• 分子名称: PROTEIN (SURFACE ANTIGEN PSAA), ZINC ION (3 entities in total)
• 機能のキーワード: psaa, abc-type binding protein, metal-binding protein, pneumococcal surface antigen, immune system
• 由来する生物種: Streptococcus pneumoniae
• 細胞内の位置: Cell membrane ; Lipid-anchor : P0A4G2
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34208.66

構造登録者

Lawrence, M.C.,Pilling, P.A.,Epa, V.C.,Berry, A.M.,Ogunniyi, A.D.,Paton, J.C. (登録日: 1998-10-13, 公開日: 2000-04-19, 最終更新日: 2023-12-27)

主引用文献

Lawrence, M.C.,Pilling, P.A.,Epa, V.C.,Berry, A.M.,Ogunniyi, A.D.,Paton, J.C.
The crystal structure of pneumococcal surface antigen PsaA reveals a metal-binding site and a novel structure for a putative ABC-type binding protein.
Structure, 6:1553-1561, 1998

PubMed Abstract: . The surface protein PsaA of the pathogenic bacterium Streptococcus pneumoniae plays an essential role in its virulence. PsaA is a putative ATP-binding cassette-type (ABC-type) binding protein involved in the uptake of Mn2+ and possibly Zn2+ and is considered to be both a potential drug target and and a candidate vaccine component.

PubMed: 9862808
DOI: 10.1016/S0969-2126(98)00153-1

実験手法

X-RAY DIFFRACTION (2 Å)