1PSP

PANCREATIC SPASMOLYTIC POLYPEPTIDE: FIRST THREE-DIMENSIONAL STRUCTURE OF A MEMBER OF THE MAMMALIAN TREFOIL FAMILY OF PEPTIDES

Summary for 1PSP

• Entry DOI: 10.2210/pdb1psp/pdb
• Descriptor: PANCREATIC SPASMOLYTIC POLYPEPTIDE (2 entities in total)
• Functional Keywords: spasmolytic protein
• Biological source: Sus scrofa (pig)
• Total number of polymer chains: 2
• Total formula weight: 23470.61

Authors

Gajhede, M.,Petersen, T.N.,Henriksen, A.,Petersen, J.F.W.,Dauter, Z.,Wilson, K.S.,Thim, L. (deposition date: 1994-01-05, release date: 1994-04-30, Last modification date: 2024-10-23)

Primary citation

Gajhede, M.,Petersen, T.N.,Henriksen, A.,Petersen, J.F.,Dauter, Z.,Wilson, K.S.,Thim, L.
Pancreatic spasmolytic polypeptide: first three-dimensional structure of a member of the mammalian trefoil family of peptides.
Structure, 1:253-262, 1993

PubMed Abstract: The trefoil peptides are a rapidly growing family of peptides, mainly found in the gastrointestinal tract. There is circumstantial evidence that they stabilize the mucus layer, and may affect the rate of healing of the mucosal epithelium.

PubMed: 8081739
DOI: 10.1016/0969-2126(93)90014-8

Experimental method

X-RAY DIFFRACTION (2.5 Å)