1PSI
Intact recombined alpha1-antitrypsin mutant PHE 51 to LEU
Summary for 1PSI
Entry DOI | 10.2210/pdb1psi/pdb |
Descriptor | ALPHA=1=-ANTITRYPSIN (1 entity in total) |
Functional Keywords | serpin, serine protease inhibitor, glycoprotein, polymorphism, emphysema, disease mutation, acute phase |
Biological source | Homo sapiens (human) |
Cellular location | Secreted. Short peptide from AAT: Secreted, extracellular space, extracellular matrix: P01009 |
Total number of polymer chains | 1 |
Total formula weight | 44406.54 |
Authors | Abrahams, J.P.,Elliott, P.R.,Lomas, D.A.,Carrell, R.W. (deposition date: 1996-06-11, release date: 1996-12-07, Last modification date: 2023-08-09) |
Primary citation | Elliott, P.R.,Lomas, D.A.,Carrell, R.W.,Abrahams, J.P. Inhibitory conformation of the reactive loop of alpha 1-antitrypsin. Nat.Struct.Biol., 3:676-681, 1996 Cited by PubMed: 8756325DOI: 10.1038/nsb0896-676 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.92 Å) |
Structure validation
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