1PRV

PURINE REPRESSOR DNA-BINDING DOMAIN DNA BINDING

Summary for 1PRV

• Entry DOI: 10.2210/pdb1prv/pdb
• Descriptor: PURINE REPRESSOR (1 entity in total)
• Functional Keywords: purine repressor, dna-binding protein, dna binding protein
• Biological source: Escherichia coli
• Total number of polymer chains: 1
• Total formula weight: 6179.13

Authors

Nagadoi, A.,Morikawa, S.,Nakamura, H.,Enari, M.,Kobayashi, K.,Yamamoto, H.,Sampei, G.,Mizobuchi, K.,Schumacher, M.A.,Brennan, R.G.,Nishimura, Y. (deposition date: 1995-05-08, release date: 1996-03-08, Last modification date: 2024-05-01)

Primary citation

Nagadoi, A.,Morikawa, S.,Nakamura, H.,Enari, M.,Kobayashi, K.,Yamamoto, H.,Sampei, G.,Mizobuchi, K.,Schumacher, M.A.,Brennan, R.G.,Nishimura, Y.
Structural comparison of the free and DNA-bound forms of the purine repressor DNA-binding domain.
Structure, 3:1217-1224, 1995

PubMed Abstract: The purine repressor (PurR) regulates genes that encode enzymes for purine biosynthesis. PurR has a two domain structure with an N-terminal DNA-binding domain (DBD) and a C-terminal corepressor-binding domain (CBD). The three dimensional structure of a ternary complex of PurR bound to both corepressor and a specific DNA sequence has recently been determined by X-ray crystallography.

PubMed: 8591032
DOI: 10.1016/S0969-2126(01)00257-X

Experimental method

SOLUTION NMR