1PQY

Crystal structure of formyl-coA transferase yfdW from E. coli

Summary for 1PQY

• Entry DOI: 10.2210/pdb1pqy/pdb
• Descriptor: Hypothetical protein yfdW (2 entities in total)
• Functional Keywords: intertwined dimer, structural genomics, psi, protein structure initiative, new york sgx research center for structural genomics, nysgxrc, unknown function
• Biological source: Escherichia coli
• Total number of polymer chains: 1
• Total formula weight: 47752.23

Authors

Gogos, A.,Gorman, J.,Shapiro, L.,Burley, S.K.,New York SGX Research Center for Structural Genomics (NYSGXRC) (deposition date: 2003-06-19, release date: 2003-09-30, Last modification date: 2024-10-30)

Primary citation

Gogos, A.,Gorman, J.,Shapiro, L.
Structure of Escherichia coli YfdW, a type III CoA transferase.
Acta Crystallogr.,Sect.D, 60:507-511, 2004

PubMed Abstract: Crystal structures are reported for free and coenzyme A (CoA) bound forms of the YfdW protein from Escherichia coli, a representative type III CoA transferase. The structures reveal a two-domain protomer with interdomain connections forming a ring-like structure with a large central hole. Two protomers associate to form a highly intertwined dimer in which the hole of each ring is filled by the partner molecule. Each protomer binds a single CoA molecule and these CoA-binding sites are distant from one another in the dimer.

PubMed: 14993676
DOI: 10.1107/S0907444904000034

Experimental method

X-RAY DIFFRACTION (2.35 Å)