1PPG

The refined 2.3 angstroms crystal structure of human leukocyte elastase in a complex with a valine chloromethyl ketone inhibitor

1PPG の概要

• エントリーDOI: 10.2210/pdb1ppg/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000414
• 分子名称: HUMAN LEUKOCYTE ELASTASE, MEO-SUCCINYL-ALA-ALA-PRO-VAL CHLOROMETHYLKETONE, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: serine proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 26670.60

構造登録者

Bode, W.,Wei, A-Z. (登録日: 1991-10-24, 公開日: 1994-01-31, 最終更新日: 2024-07-10)

• 主引用文献: Wei, A.Z.,Mayr, I.,Bode, W.; The refined 2.3 A crystal structure of human leukocyte elastase in a complex with a valine chloromethyl ketone inhibitor.; FEBS Lett., 234:367-373, 1988; PubMed: 3391280; DOI: 10.1016/0014-5793(88)80118-2

実験手法

X-RAY DIFFRACTION (2.3 Å)