Crystal structure of human glutathione transferase (GST) A1-1

Summary for 1PKZ

Related1PKW 1PL1 1PL2
DescriptorGlutathione S-transferase A1, 2-HYDROXYETHYL DISULFIDE (3 entities in total)
Functional Keywordsdomain1:alpha beta, domain2:alpha-helical, transferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm P08263
Total number of polymer chains2
Total molecular weight51680.74
Grahn, E.,Jakobsson, E.,Gustafsson, A.,Grehn, L.,Olin, B.,Wahlberg, M.,Madsen, D.,Kleywegt, G.J.,Mannervik, B. (deposition date: 2003-06-06, release date: 2004-06-22, Last modification date: 2018-03-07)
Primary citation
Grahn, E.,Novotny, M.,Jakobsson, E.,Gustafsson, A.,Grehn, L.,Olin, B.,Madsen, D.,Wahlberg, M.,Mannervik, B.,Kleywegt, G.J.
New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix.
Acta Crystallogr.,Sect.D, 62:197-207, 2006
PubMed: 16421451 (PDB entries with the same primary citation)
DOI: 10.1107/S0907444905039296
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23140.2%4.5%4.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution