1PG1

PROTEGRIN 1 (PG1) FROM PORCINE LEUKOCYTES, NMR, 20 STRUCTURES

1PG1 の概要

• エントリーDOI: 10.2210/pdb1pg1/pdb
• 分子名称: PROTEGRIN-1 (1 entity in total)
• 機能のキーワード: antimicrobial peptide
• 由来する生物種: Sus scrofa (pig)
• 細胞内の位置: Secreted: P32194
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 2164.68

構造登録者

Fahrner, R.L.,Dieckmann, T.,Harwig, S.S.L.,Lehrer, R.I.,Eisenberg, D.,Feigon, J. (登録日: 1998-03-20, 公開日: 1998-05-27, 最終更新日: 2024-11-20)

主引用文献

Fahrner, R.L.,Dieckmann, T.,Harwig, S.S.,Lehrer, R.I.,Eisenberg, D.,Feigon, J.
Solution structure of protegrin-1, a broad-spectrum antimicrobial peptide from porcine leukocytes.
Chem.Biol., 3:543-550, 1996

PubMed Abstract: The protegrins are a family of arginine- and cysteine-rich cationic peptides found in porcine leukocytes that exhibit a broad range of antimicrobial and antiviral activities. They are composed of 16-18 amino-acid residues including four cysteines, which form two disulfide linkages. To begin to understand the mechanism of action of these peptides, we set out to determine the structure of protegrin-1 (PG-1).

PubMed: 8807886
DOI: 10.1016/S1074-5521(96)90145-3

実験手法

SOLUTION NMR