1P7Q

Crystal Structure of HLA-A2 Bound to LIR-1, a Host and Viral MHC Receptor

1P7Q の概要

• エントリーDOI: 10.2210/pdb1p7q/pdb
• 分子名称: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, POL polyprotein, ... (4 entities in total)
• 機能のキーワード: hla-a2-lir-1 complex, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01892 Q8NHL6; Secreted: P61769; Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12499
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 66691.32

構造登録者

Willcox, B.E.,Thomas, L.M.,Bjorkman, P.J. (登録日: 2003-05-05, 公開日: 2003-10-14, 最終更新日: 2023-08-16)

• 主引用文献: Willcox, B.E.,Thomas, L.M.,Bjorkman, P.J.; Crystal structure of HLA-A2 bound to LIR-1, a host and viral major histocompatibility complex receptor.; Nat.Immunol., 4:913-919, 2003; PubMed: 12897781; DOI: 10.1038/ni961

実験手法

X-RAY DIFFRACTION (3.4 Å)