1P6N

Bovine endothelial NOS heme domain with L-N(omega)-nitroarginine-(4R)-amino-L-proline amide bound

Summary for 1P6N

Related1P6H 1P6I 1P6J 1P6K 1P6L 1P6M
DescriptorNitric-oxide synthase, endothelial, CACODYLATE ION, ACETATE ION, ... (9 entities in total)
Functional Keywordsnitric oxide synthase, oxidoreductase, heme-enzyme
Biological sourceBos taurus (cattle)
Cellular locationCell membrane P29473
Total number of polymer chains2
Total molecular weight96984.23
Authors
Flinspach, M.L.,Li, H.,Jamal, J.,Yang, W.,Huang, H.,Hah, J.-M.,Gomez-Vidal, J.A.,Litzinger, E.A.,Silverman, R.B.,Poulos, T.L. (deposition date: 2003-04-29, release date: 2004-01-13, Last modification date: 2011-07-13)
Primary citation
Flinspach, M.L.,Li, H.,Jamal, J.,Yang, W.,Huang, H.,Hah, J.M.,Gomez-Vidal, J.A.,Litzinger, E.A.,Silverman, R.B.,Poulos, T.L.
Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11:54-59, 2004
PubMed: 14718923 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb704
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.257191.6%2.6%3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution