1P6M

Bovine endothelial NOS heme domain with (4S)-N-(4-amino-5-[aminoethyl]aminopentyl)-N'-nitroguanidine bound

Summary for 1P6M

Entry DOI	10.2210/pdb1p6m/pdb
Related	1P6H 1P6I 1P6J 1P6K 1P6L 1P6N
Descriptor	Nitric-oxide synthase, endothelial, CACODYLATE ION, ACETATE ION, ... (9 entities in total)
Functional Keywords	nitric oxide synthase, oxidoreductase, heme-enzyme
Biological source	Bos taurus (cattle)
Cellular location	Cell membrane: P29473
Total number of polymer chains	2
Total formula weight	96818.14
Authors	Flinspach, M.L.,Li, H.,Jamal, J.,Yang, W.,Huang, H.,Hah, J.-M.,Gomez-Vidal, J.A.,Litzinger, E.A.,Silverman, R.B.,Poulos, T.L. (deposition date: 2003-04-29, release date: 2004-01-13, Last modification date: 2024-02-14)
Primary citation	Flinspach, M.L.,Li, H.,Jamal, J.,Yang, W.,Huang, H.,Hah, J.M.,Gomez-Vidal, J.A.,Litzinger, E.A.,Silverman, R.B.,Poulos, T.L. Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase. Nat.Struct.Mol.Biol., 11:54-59, 2004 Cited by PubMed: 14718923 DOI: 10.1038/nsmb704 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.27 Å)

Structure validation